Question regarding CTAs

For CTAs, can anyone submit a CTA? Meaning can a US company submit a CTA to different countries without having in-country representation? (i.e. can a US only company submit CTAs to the Netherlands, Spain, Germany and UK without having an EU contact sign off?)

Any guidance would be extremely helpful.

thank you!

The simple answer is no, you will need a legal representative based in the EU.
Happy to discuss further

This is the exact confirmation I needed - thank you so much!!!